Objective. To investigate the feasibility and safety of higher-dose dexmedetomidine in ophthalmological outpatient examination of\nchildren with cataract. Methods. 100 cases of children were recruited in the study and randomly equally divided into two groups.\nOne group was given 2 microg/kg intranasal dexmedetomidine anesthesia, while the other group was under 3 microg/kg. The dosage of\ndexmedetomidine was calculated by the same anesthesiologist according to the weight of patient. After sufficient sedation, the\nsame ophthalmologist performed ocular examinations manually, including intraocular pressure, keratometry, axial length, and\ncorneal thickness and recorded the ocular position score during intraocular pressure measurement and corneal thickness\nmeasurement. Other variables were sedation onset time, recovery time, vital signs, and side effects. Results. In intraocular pressure\nmeasurement, only one case in the 2 microg/kg group did not complete the examination, while all cases in the 3 microg/kg group completed\nthe examination and the difference of the success rate between the two groups was nonsignificant (P > 0.05). The success rates of\nthe 3 microg/kg group in corneal curvature, axial length, and corneal thickness examination were 96%, 92%, and 86%, respectively,\nwhich were significantly higher than those of the 2 microg/kg group (22%, 18%, and 4%).Theaverage onset time of sedation in the 3 microg/\nkg group was................
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